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For chronic urticaria, adults and children 12 years or older should use 60 mg twice daily, and children 6-11 years of age should use 30 mg twice daily. Fexofenadine can be taken with or without food.
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Drug Class and Mechanism - Fexofenadine is an oral, "second generation" antihistamine that is used to treat the signs and symptoms of allergy that are due to histamine.
It is similar to the other second generation antihistamines loratadine (Claritin), cetirizine (Zyrtec) and azelastine (Astelin). Histamine is a chemical that is responsible for many of the signs and symptoms of allergic reactions, for example, swelling of the lining of the nose, sneezing, and itchy eyes.
Histamine is released from histamine-storing cells (mast cells) and then attaches to other cells that have receptors for histamine. The attachment of the histamine to the receptors causes the cell to be "activated," releasing other chemicals that produce the effects that we associate with allergy, e.g., sneezing.
Fexofenadine blocks one type of receptor for histamine (the H1 receptor) and thus prevents activation of H1 receptor-containing cells by histamine.
Unlike the first generation antihistamines, fexofenadine and other second-generation antihistamines do not readily enter the brain from the blood, and, therefore, they cause less drowsiness. Fexofenadine was approved by the FDA in July, 1995..
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If you miss a dose of Clarinex and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.
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How to use - To treat asthma symptoms such as wheezing, breathlessness and tightness in your chest, a usual dose is:
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* Adults: One or two puffs to relieve symptoms or two puffs 10-15 minutes before exercise or exposure to a trigger.
* Children: One or two puffs to relieve symptoms or 10-15 minutes before exercise or exposure to a trigger.
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How to use - Take this medication by mouth usually once daily, with or without food, or as directed by your doctor. This drug is best taken in the evening. Dosage is based on your medical condition, response to therapy, and use of certain interacting medicines. Many of the drugs listed in the Drug Interactions section may increase the chances of muscle injury when used with pravachol. Consult your doctor or pharmacist for more details.
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Diovan may also reduce hospitalizations in patients with congestive heart failure.
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How to use - The usual dose of diovan in patients with high blood pressure is 80 to 160 mg once daily. The maximum dose is 320 mg daily. Maximum blood pressure reduction occurs within 4 weeks. For congestive heart failure, the usual dose is 40 mg twice daily. The doses may be increased to 80-160 mg twice daily.
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Drug Class and Mechanism - Phenergan is a phenothiazine antihistamine. It works by blocking the sites where histamine acts.
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Drug Name - Sustiva (Efavirenz)
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Drug Uses - This medication is used to treat HIV infection in combination with other anti-HIV medications. If sustiva is the only drug you take to treat HIV infection, it may stop working.
Consult your doctor or pharmacist for more details.
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How to use - Take this drug by mouth, generally once daily as directed. Take on an empty stomach with a glass of water. Taking sustiva with food, especially a high-fat meal can lead to increased blood levels of the drug and increase your risk of having side effects. Best taken at bedtime during the first month of use. Using this drug regularly at bedtime may decrease certain side effects.
Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not take more or less of this drug than prescribed, or stop taking it unless directed to do so by your doctor.
Read the patient information leaflet provided by your pharmacist.
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Drug Class and Mechanism - Sustiva is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is similar to nevirapine (Viramune) and delavirdine (Rescriptor). Sustiva is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated.
When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Sustiva directly inhibits the activity of reverse transcriptase and blocks the production of DNA and new viruses. Unlike zidovudine, efavirenz does not need to be converted to an active form. Sustiva does not kill existing HIV virus and it is not a cure for HIV.
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